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All applicationsC–C & C–N BOND FORMATION

Palladium catalysts for cross-coupling

Match palladium catalyst and ligand systems to the coupling partners, selectivity requirement and process conditions.

START WITH THE PROCESS

These inputs help SWC avoid a generic product response.

Coupling partners and leaving group

Identify both coupling partners and the leaving group, such as a halide or triflate.

Target yield and impurity limits

State the yield you achieve today and the impurity limits the product must meet.

Base, solvent and temperature

Describe the base, solvent and temperature in use, and any that are ruled out.

Residual-metal requirement

Give the maximum residual palladium allowed in the isolated product.

CANDIDATE CHEMISTRY

Final suitability is confirmed against the complete technical brief.

EVALUATION PATH

  1. Share the transformation
  2. Map catalyst and ligand options
  3. Run a focused evaluation
  4. Optimise and transfer
READY FOR A FOCUSED DISCUSSION?

Your selected application is carried into the enquiry so you do not need to explain the context again.