(R)-BNP Acid

(R)-BNP Acid

Chiral Catalysts, Ligands, Reagents, Privileged Ligands and Complexes, Asymmetric Synthesis, Chemical Synthesis, Chiral Resolving Agents, and Chiral Resolution Agents, and Chiral Phosphoric Acids

Applications :

 (R)-BNP Acid is a versatile reagent having several applications: 

1) As an organocatalyst to facilitate controlled ring-opening homopolymerization and copolymerization of ε-caprolactone (cyclic ester) (Ref: Colloid and Polymer Science 291(9), 2155-2162, (2013))

2) As an additive to a copper based catalyst to achieve the highest catalytic activity in Sonogashira-type reactions (Ref:  Applied Organometallic Chemistry 29(5), 301-304, (2015))

3) As a chiral ligand in hydrocarboxylation reactions (Ref: Journal of the American Chemical Society 112, 2803-2803, (1990))

4) As a chiral ligand in asymmetric dipolar cycloaddition of diazo compounds (Ref: Tetrahedron Letters 33, 5987-5987, (1992))

5)  As an acidic resolving agent for certain amine/racemic mixtures (Ref:J. Org. Chem., 1991, 56, 485; US 6,162,919.)