(S)-BINAP

(S)-BINAP

Asymmetric Synthesis, BINAPs, Chemical Synthesis, Chemicals for the synthesis of candidate COVID-19 treatments, Chiral Catalysts, Ligands, and Reagents, Nelfinavir Mesylate, Privileged Ligands and Complexes

Applications: 

1) (S)-BINAP or (S)-Tol-BINAP when combined with dichloro(1,5-cyclooctadiene)ruthenium, form precursors to Noyori Catalyst Systems which exhibit very high catalytic activity and enantioselectivity in the hydrogenation of a wide range of substrates. For example, Noyori Catalyst Systems are highly enantioselective in the hydrogenation of functionalized ketones containing dialkylamino, hydroxy, siloxy, carbonyl, ester, amide or thioester substituents (Ref: CHEMTECH, 1992, 360)

2. Useful ligand in asymmetric Heck processes (Ref: Asymmetric Catalysis in Organic Synthesis, 1993, 61)